:: Volume 17, Number 2 (Basic Science Issue - February 2015) ::
ZJRMS 2015, 17(2): 42-46 Back to browse issues page
The Effects of Aqueous Extract of Anacyclus Pyrethrum on Sperm Count and Reproductive Organs in Adult Male Rats
Mohammad Reza Shahraki, Sarieh Shahraki , Mohammad Reza Arab, Mahnaz Shahrakipour
Department of Physiology, Zahedan University of Medical Sciences, Zahedan, Iran , Sariehshahraki@yahoo.com
Abstract:   (5813 Views)
Background : More than 80 million individuals suffer from infertility globally. Various factors such as some drugs and toxins have harmful effects on fertility. Anacyclus pyrethrum plant in Indian traditional medicine is used for treatment of many diseases including infertility.
Materials and Methods :  In this experimental study 48 male adult rats were divided randomly into four groups (N=12) including one control group (A) and three test groups (B, C and D). Test groups (B, C and D) received root aqueous extract of A. pyrethrum intraperitoneally with doses of 50, 100 and 150 mg/kg for 28 days, respectively. At the end of the treatment period, the reproduction variables such as weight of body and sex organs, the sperm count in epididymis and right and left vas deferens and percent of abnormal spermatozoids were determined. The test groups were compared to the controls using analysis of variance following Tukey.
Results : Data analysis of body and sex organs’ weight, sperm count of epididymis and right and left vas deferens and percent of abnormal spermatozoids showed a significant difference between the tests and control groups (p=0.02, p=0.0001) however, no significant difference was found between two groups regarding vas deferens weight.
Conclusion : The results of the present study showed that root aqueous extract of A. pyrethrum increased the weights of body and sex organs, increase of sperm count of epididymis and right and left vas deferens, and reduction of percent of abnormal spermatozoids in treated rats.
Keywords: Anacyclus pyrethrum, Epididymis, Spermatogenesis
Full-Text [PDF 131 kb]   (2376 Downloads)    
Type of Study: Research | Subject: Physiology



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Volume 17, Number 2 (Basic Science Issue - February 2015) Back to browse issues page