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ZJRMS 2015, 17(1): 15-18 Back to browse issues page
Frequency of Antitoxocara Antibodies in Students with Chronic Cough and Eosinophilia in a Rural Area of Shiraz, Iran
Ali Ghorbani-Ranjbary , Nazanin Ghorbani-Ranjbary , Sara Varzandian , Zahra Ghorbani-Ranjbary
Young Researchers and Elite Club, Kazerun Branch, Islamic Azad University, Kazerun, Iran , dr_alighorbani87@yahoo.com
Abstract:   (7344 Views)
Background : Visceral larva migrant’s syndrome by toxocara affects mainly children between 2 and 5 years old, it is generally asymptomatic, and the seroprevalence varies from 3 to 86% in different countries as well as, the secondary stage larvae cause ocular, respiratory and neurotic disorders. The aim of this study was to determine the incidence of anti-toxocara antibodies in children blood that showed chronic cough having eosinophilia in rural part of Shiraz, Iran.
Materials and Methods : In a cross sectional study during a tuberculin survey rural area of Shiraz, a city in Southwest Iran, a number of 610 children were selected by randomized two-stage cluster sampling. Children with chronic cough were investigated for toxocariasis. Initially, the absolute eosinophil count was determined. Then, children having eosinophilia were tested by toxocara-IgG - ELISA kit (Ibl, Hamburg).
Results : Of total 80 children with chronic cough, 12 (15%) were eosinophilic, among them 6.25% were hypereosinophilic, 9 (11.25%) were toxocara ELISA-IgG positive. No correlation between intestinal parasites and toxocariasis was detected. There was also no significant interdependence between age, gender, and dwelling difference in toxocara antibody amount.
Conclusion : Presence of eosinophilia and the risk factors evaluated in this population were frequently associated to human toxocariasis. Anti toxocara antibody was detected in more than half of children with chronic cough, thus, toxocariasis among children in schools should have been noticed in schools by both education and hygiene ministry.
Keywords: Toxocariasis, Toxocara cati, Anti-toxocara antibody, Eosinophilia, Chronic cough
Full-Text [PDF 78 kb]   (1414 Downloads)    
Type of Study: Research | Subject: Immunology
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Ghorbani-Ranjbary A, Ghorbani-Ranjbary N, Varzandian S, Ghorbani-Ranjbary Z. Frequency of Antitoxocara Antibodies in Students with Chronic Cough and Eosinophilia in a Rural Area of Shiraz, Iran . ZJRMS. 2015; 17 (1) :15-18
URL: http://zjrms.ir/article-1-2960-en.html

Volume 17, Issue 1 (Clinical Science Issue - January 2015) Back to browse issues page
Zahedan Journal of Research in Medical Sciences
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