:: Volume 16, Issue 1 (Clinical Science Issue -January 2014) ::
ZJRMS 2014, 16(1): 13-16 Back to browse issues page
Comparison of Serum CRP in Migraine Sufferers and Normal Population
Hosseinali Salehi, Mohammad Aminianfar , Alireza Ranjbar-Naeeni, Aliasghar Saidi, Fariba Rastgoo
, maminianfar@yahoo.com
Abstract:   (5180 Views)
Background : CRP (C-reactive protein) is one of the known inflammatory markers in the body. Studies claim that the level of this marker in patients with migraine is higher than normal peoples. Despite the result of various studies, even the relation between serum CRP and migraine is not detected thoroughly and is in a halo of ambiguity, therefore in this study, we intended to assess the relation between migraine and serum CRP levels.
Materials and Methods : The present study was performed as a case-control on 47 migraine suffers that presented Besat hospital on year 2011, at intervals between their attacks and 50 normal individuals. Serum CRP level was measured at interval between attacks or at least 72 hour after the completion of the last attack and was compared with obtained results from normal population.
Results : The comparison of CRP level in two groups, indicated that the median CRP at case group was 16.40 mg/dl and at control group 9.76 mg/dl (p≤0.05). The comparison of CRP median between the sufferers of classic migraine, migraine without aura and individuals without migraine, indicated that the CRP median difference at without aura migraine sufferers and normal population was not meaningful, but classic migraine suffers had higher serum CRP level than the other two groups.
Conclusion : Finally, we should stay that the present study demonstrate that CRP inflammatory marker was higher at migraine suffers in comparison with normal general population and could explained the role of inflammation in creation and progression of this type of headache.
Keywords: Migraine headache, Cerebral arteries, Inflammation
Full-Text [PDF 104 kb]   (1654 Downloads)    
Type of Study: Research | Subject: Neurology
* Corresponding Author Address: Department of Infectious and Tropical disease, AJA University of Medical Sciences, Tehran, Iran

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Volume 16, Issue 1 (Clinical Science Issue -January 2014) Back to browse issues page