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:: Volume 15, Issue 6 (Basic Science Issue - June 2013) ::
ZJRMS 2013, 15(6): 29-33 Back to browse issues page
Efficacy of a Combined Rosemary and Lavender Topical Ointment in the Treatment of Patients with Osteoarthritis of the Knee
Alireza Ghannadi , Hadi Karimzadeh , Naser Tavakoli , Mohammad Darafsh , Paria Ramezanloo
, ghannadi@pharm.mui.ac.ir
Abstract:   (7139 Views)
Background : One of the preservative treatments of knee osteoarthritis is the use of topical medications. This study is aimed to clinically evaluate the effect of topical products containing essential oils of rosemary and lavender herbs on the treatment of patients with osteoarthritis of the knee.
Materials and Methods : Rosemary and lavender essential oils were prepared by steam distillation method and inserted into the ointment with the hydrophilic base. In this study, 15 patients with knee osteoarthritis were treated with this ointment for three months. The results were assessed using WOMAC and Lequesne indices and were evaluated by the Wilcoxon statistical test.
Results : At the week of admission to the hospital, mean WOMAC index was equal to 71.4, mean Lequesne index was equal to 18 and the average time of passing through the distance of fifty feet by patients was equal to 19.4. After 4, 8 and 12 weeks, all these indices significantly decreased (p≤ 0.05). The WOMAC questionnaire denotative survey also showed that the pain and physical function at the 4th, 8th and 12th weeks were significantly less than the first week of admission (p≤ 0.05), but there was no significant difference as far as joint stiffness is concerned.
Conclusion : Topical application of essential oils of rosemary and lavender herbs in a hydrophilic ointment base can be useful as a preservative treatment for the patients with knee osteoarthritis.
Keywords: Knee osteoarthritis, Topical products, Rosemary, Lavender, Pain
Full-Text [PDF 134 kb]   (2609 Downloads)    
Type of Study: Research | Subject: Rheumatology
* Corresponding Author Address: Department of Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences Research Centre, Isfahan University of Medical Sciences, Isfahan, Iran
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Ghannadi A, Karimzadeh H, Tavakoli N, Darafsh M, Ramezanloo P. Efficacy of a Combined Rosemary and Lavender Topical Ointment in the Treatment of Patients with Osteoarthritis of the Knee. ZJRMS. 2013; 15 (6) :29-33
URL: http://zjrms.ir/article-1-1741-en.html


Volume 15, Issue 6 (Basic Science Issue - June 2013) Back to browse issues page
Zahedan Journal of Research in Medical Sciences
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