[Home ] [Archive]   [ فارسی ]  
:: Main Online Submission Archive Current Issue In Press ::
:: Volume 15, Issue 8 (Basic Science Issue - August 2013) ::
ZJRMS 2013, 15(8): 13-17 Back to browse issues page
The Effects of Hydro-Alcoholic Extract of Zingiber Officinale on Prevention from Plumbism in Kidney Tissue of Neonatal Rats
Habiballah Johari , Fatemeh Delirnasab , Esfandiar Sharifi , Vahid Hemayat-Khah , Mohammadali Pourdanesh , Hosein Kargar , Maryam Nikpour , Mohammad Yazdani
, hjowhary@yahoo.co.uk
Abstract:   (5221 Views)
Background : In the present research, the effects of hydro-alcoholic extract of zingiber officinale (ginger) on treating lead-poisoned kidney of neonatal rats was studied.
Materials and Methods : This research was conducted as a laboratory work. The neonatal rats were divided into 7 groups of 10 samples. The first control group received no treatment. The second control group received 0.1 mg of distilled water. As an experimental group, the one received an amount of 0.6 g/l lead. The fourth group received only 2 g/kg body weight of hydro-alcoholic extract of ginger. Groups 5 to 7 each initially received 0.6 g/l lead and then amounts of 0.5, 1 and 2 g/kg hydro-alcoholic extract of ginger. The injections were administered via oral gavage during 10 consecutive days.
Results : According to the obtained results, the body and kidney weights showed a significant reduction in experimental groups that had received amounts of 1 and 2 g/kg in comparison with the group that had received lead. The kidney weight of the group that had received only extract showed no significant difference in comparison with the control group. As for the body weights, however, it showed a significant increase. Moreover, the body and kidney weights of the lead-injected group showed a significant increase in comparison with the control group.
Conclusion : Lead can cause damage to kidney tissues. Due to its antioxidant and protective effect, ginger can be a medication to nephrotoxicity of lead and prevent kidney tissues from destruction.
Keywords: Zingiber officinale (ginger), Lead, Kidney, Rats, Poisoning
Full-Text [PDF 316 kb]   (1554 Downloads)    
Type of Study: Research | Subject: Physiology
* Corresponding Author Address: Department of Physiology, Darab Branch, Islamic Azad University, Darab, Iran
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA code


XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Johari H, Delirnasab F, Sharifi E, Hemayat-Khah V, Pourdanesh M, Kargar H, et al . The Effects of Hydro-Alcoholic Extract of Zingiber Officinale on Prevention from Plumbism in Kidney Tissue of Neonatal Rats. ZJRMS. 2013; 15 (8) :13-17
URL: http://zjrms.ir/article-1-1625-en.html


Volume 15, Issue 8 (Basic Science Issue - August 2013) Back to browse issues page
Zahedan Journal of Research in Medical Sciences
Persian site map - English site map - Created in 0.05 seconds with 31 queries by YEKTAWEB 3742