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ZJRMS 2012, 14(3): 29-33 Back to browse issues page
The Effect of 217 Hz Magnetic Field of Cell Phone with Different Intensities on Apoptosis of Normal and Cancerous Cells Treated with Chemotherapy Drug
Mahsa Mansourian , S. Mohammad Firoozabadi , Zuhair Mohammad Hassan , Zeynab Shankayi
, pourmir@modares.ac.ir
Abstract:   (8978 Views)

Background: According to the increasing development of home and business electronic equipment in today's world, the biological effects of ELF magnetic fields have been studied at two molecular-cellular and animal- human levels. Considering the therapeutic viewpoint of this study regarding the effects of low-frequency fields of mobile phone, the effect of acute exposure to this field on chemotherapy will be studied.
Materials and Methods: In this experimental study, based on measurement of the intensity of the magnetic fields from mobile phones in another research, flux densities of magnetic field of 159.44, 93.25 and 120µ tesla with frequency of 217Hz was generated in magnetic field generator system, and the apoptosis level in K562 cancer cells and healthy cells of lymphocytes was assessed after exposure to field using flow cytometry method. This evaluation method was also performed for the cells treated with bleomycin after exposure to this field.
Results: 217 Hz magnetic field exposure significantly increases the rate of apoptosis percentage (p > 0.05) in K562 cancer cells and in two intensities of 120 and 159.44µ tesla compared to the control group, but such effect is not observed in lymphocyte cells. Bleomycin-induced apoptosis percentage following exposure to the mentioned magnetic field shows no significant difference compared to the group of treatment with drug and without field exposure. This lack of significant difference is observed between the groups of drug after field exposure and field alone as well as between groups exposed to field and groups treated with bleomycin.
Conclusion: Study results showed that 217 Hz magnetic field of mobile phone can induce apoptosis on cancer cells, but it has no effect on healthy cells. Thus, in order to use mobile phone as an effective factor in their treatment, some studies should be conducted at animal-human level.

Keywords: Magnetic field therapy, Apoptosis, Bleomycin
Full-Text [PDF 322 kb]   (2185 Downloads)    
Type of Study: Research | Subject: Medical physics
* Corresponding Author Address: Department of Medical Physics, Tarbiat Modares University, Tehran, Iran
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Mansourian M, Firoozabadi S M, Mohammad Hassan Z, Shankayi Z. The Effect of 217 Hz Magnetic Field of Cell Phone with Different Intensities on Apoptosis of Normal and Cancerous Cells Treated with Chemotherapy Drug. ZJRMS. 2012; 14 (3) :29-33
URL: http://zjrms.ir/article-1-1197-en.html

Volume 14, Issue 3 (Basic Science Issue - May 2012) Back to browse issues page
Zahedan Journal of Research in Medical Sciences
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