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ZJRMS 2014, 16(10): 10-14 Back to browse issues page
The Comparison of Acceptance and Commitment Therapy with Selective Serotonin Reuptake Inhibitors in the Treatment of Obsessive-Compulsive Disorder
Yaghoob Vakili , Banafsheh Gharraee , Mojtaba Habibi , Fahimeh Lavasani , Maryam Rasoolian
Department of Clinical Psychology, Tehran Institute of Psychiatry, Faculty of Behavioral Sciences and Mental Health, Iran University of Medical Sciences, Tehran, Iran , BGHARAEE@TUMS.AC.IR
Abstract:   (6072 Views)
Background : The aim of this study was to compare the effectiveness of acceptance and commitment therapy (ACT), selective serotonin reuptake inhibitors (SSRIs), and the combination of ACT and SSRIs in the treatment of adults with obsessive-compulsive disorder (OCD).
Materials and Methods : In This experimental study 32 outpatients meeting DSM-IV-TR criteria for OCD were randomly assigned to one of three treatment conditions: ACT, SSRIs, and combined treatment. The Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Beck Depression Inventory-II-Second edition (BDI-II), and Beck Anxiety Inventory (BAI) were administered at pre- and post-treatment. Twenty-seven patients completed the study. Data were analyzed by one-way analysis of variance (ANOVAs) and one - way analysis of covariance (ANCOVAs), clinically significant change, and complete remission status.
Results :
Analyses with ANCOVA revealed that the patients treated with ACT and combined treatment experienced a significantly greater improvement in obsessive- compulsive symptoms at post-treatment as compared to those treated with SSRIs alone. However, there were no significant differences between ACT and combined treatment on OC symptoms. In addition, no significant differences were found between all the 3 treatment groups regarding reduction in the BDI-II and BAI scores at post-treatment. Clinically significant change and complete remission status results also showed that, unlike the SSRI, the ACT and combined treatment lead to more improvement in OC symptoms.
Conclusion :
ACT and combined treatment are more effective than SSRIs alone in treating OC symptoms. However, it seems that adding SSRIs to ACT does not increase the effectiveness of ACT in the treatment of adults with OCD in the short-term.
Keywords: Obsessive-compulsive disorder, Acceptance and commitment therapy, Serotonin reuptake inhibitors
Full-Text [PDF 144 kb]   (1334 Downloads)    
Type of Study: Research | Subject: Psychology
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Vakili Y, Gharraee B, Habibi M, Lavasani F, Rasoolian M. The Comparison of Acceptance and Commitment Therapy with Selective Serotonin Reuptake Inhibitors in the Treatment of Obsessive-Compulsive Disorder. ZJRMS. 2014; 16 (10) :10-14
URL: http://zjrms.ir/article-1-2992-en.html


Volume 16, Issue 10 (Supplement 1- October 2014) Back to browse issues page
Zahedan Journal of Research in Medical Sciences
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